An expert review of published data on experiences with doxycycline use during pregnancy by TERIS the Teratogen Information System concluded that therapeutic doses during pregnancy are unlikely to pose a substantial teratogenic risk the quantity and quality of data were assessed as limited to fair, but the data are insufficient to state that there is no risk 8 lasix side effect Animal research frequently involves the use of hazardous chemicals such as carcinogens, reproductive toxins or other highly toxic substances